Polymicrobial Interactions Induce Multidrug Tolerance in Staphylococcus aureus Through Energy Depletion
Staphylococcus aureus is responsible for a high number of relapsing infections, which are often mediated by the protective nature of biofilms.Polymicrobial biofilms appear to be more tolerant to antibiotic treatment, however, the underlying mechanisms for this remain unclear.Polymicrobial biofilm and planktonic cultures formed by S.aureus and Candi